Step 1 :Let $u = -x$. Then, $x = -u$ and $d x = -d u$. Also, when $x = -2$, $u = 2$, and when $x = 2$, $u = -2$.
Step 2 :Substitute $u$ into the integral: $\int_{-2}^{2} \frac{x^{2}}{e^{x}+1} d x = -\int_{2}^{-2} \frac{u^{2}}{e^{u}+1} d u$.
Step 3 :Evaluate the integral: $\int_{-2}^{2} \frac{x^{2}}{e^{x}+1} d x = -\int_{2}^{-2} \frac{u^{2}}{e^{u}+1} d u$.
Step 4 :\(\boxed{-\int_{2}^{-2} \frac{u^{2}}{e^{u}+1} d u}\)