Step 1 :Interpret the expression as the opposite of $16^{\frac{3}{4}}$ which can be expressed as $-[(\sqrt[4]{16})^{3}]$
Step 2 :Calculate the fourth root of 16, which is 2.0
Step 3 :Raise the result to the power of 3, which gives 8.0
Step 4 :Negate the result to get the final answer, which is -8.0
Step 5 :Final Answer: \(\boxed{-8.0}\)