Step 1 :Simplify the given expression by combining like terms: $16x^2 + 8x - 6x - 3$
Step 2 :Combine the like terms: $16x^2 + (8x - 6x) - 3$
Step 3 :Calculate the result: $16x^2 + 2x - 3$
Step 4 :\(\boxed{16x^2 + 2x - 3}\)